The Challenges of Vaccine Growth in opposition to Betacoronaviruses: Antibody Dependent Enhancement and Sendai Virus as a Attainable Vaccine Vector
To design an efficient and protected vaccine in opposition to betacoronaviruses, it’s crucial to make use of their evolutionarily conservative antigenic determinants that may elicit the mix of robust humoral and cell-mediated immune responses. Focusing on such determinants minimizes the chance of antibody-dependent enhancement of viral an infection. This phenomenon was noticed in animal trials of experimental vaccines in opposition to SARS-CoV-1 and MERS-CoV that have been developed based mostly on inactivated coronavirus or vector constructs expressing the spike protein (S) of the virion.
The substitution and glycosylation of sure amino acids within the antigenic determinants of the S-protein, in addition to its conformational adjustments, can result in the identical impact in a brand new experimental vaccine in opposition to
SARS-CoV-2. Utilizing extra conservative structural and accent viral proteins for the vaccine antigenic determinants will assist to keep away from this drawback.
This evaluation outlines approaches for creating vaccines in opposition to the brand new SARS-CoV-2 coronavirus which might be based mostly on non-pathogenic viral vectors. For environment friendly prevention of infections attributable to respiratory
pathogens the flexibility of the vaccine to stimulate mucosal immunity within the respiratory tract is essential. Such a vaccine might be developed utilizing non-pathogenic Sendai virus vector, since it may be administered intranasally and induce a mucosal immune response that strengthens the antiviral barrier within the respiratory tract and offers dependable safety in opposition to an infection.
Growth of Excessive Decision DNA Melting Evaluation for Simultaneous Detection of Potato Mop-High Virus and Its Vector , Spongospora subterranea, in Soil
On this examine, a set of duplex reverse transcription (RT)-PCR-mediated excessive decision
DNA melting (HRM) analyses for simultaneous detection of potato mop-virus (PMTV) and its protist vector, Spongospora subterranea f.sp. subterranea (Sss), was developed. The infestation of soil by PMTV was detected through the use of a tobacco-based baiting system. Complete RNA extracted from the soil led to profitable RT-PCR gel-electrophoresis detection of each PMTV and Sss.
To facilitate extra environment friendly detection, newly designed primer pairs for
PMTV RNA species (i.e., RNA-Rep, -CP, and -TGB) have been analyzed along with the present Sss primers utilizing real-time RT-PCR. The ensuing amplicons exhibited melting profiles that might be readily differentiated.
Below duplex RT-PCR format, all PMTV and Sss primer mixtures led to profitable detection of respective
PMTV RNA species and Sss within the samples by excessive decision DNA melting (HRM) analyses. When the duplex HRM assay was utilized to soil samples collected from six fields at 4 completely different websites in New Brunswick, Canada, optimistic detection of PMTV and/or Sss was present in 63-100% samples collected from fields through which PMTV-infected tubers had been noticed.
In distinction, the samples from fields the place neither PMTV- nor Sss-infected tubers had been noticed resulted in damaging detection by the assay. Bait tobacco bioassay for
PMTV and Sss produced related outcomes . Between 63%-83% and 100% of the soil samples collected from PMTV-infested fields led to PMTV and Sss infections within the bait tobacco crops, respectively; whereas no PMTV or Sss contaminated crops have been obtained from soil samples collected from PMTV/Sss-free fields.
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Hes5 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL711044
Origene Technologies GmbH
5 µg/vial
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HES5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL312477
Origene Technologies GmbH
5 µg/vial
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Hes5 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL500948
Origene Technologies GmbH
5 µg/vial
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HES7 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV623137
ABM
1.0 ug DNA
EUR 616.8
HES7 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV623141
ABM
1.0 ug DNA
EUR 616.8
HES3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV672265
ABM
1.0 ug DNA
EUR 616.8
HES3 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV672269
ABM
1.0 ug DNA
EUR 616.8
HES2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV672367
ABM
1.0 ug DNA
EUR 616.8
HES2 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV672371
ABM
1.0 ug DNA
EUR 616.8
HES1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV686503
ABM
1.0 ug DNA
EUR 616.8
HES1 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV686507
ABM
1.0 ug DNA
EUR 616.8
HES7 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
LV623142
ABM
1.0 ug DNA
EUR 616.8
HES3 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
LV672270
ABM
1.0 ug DNA
EUR 616.8
HES2 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
LV672372
ABM
1.0 ug DNA
EUR 616.8
HES1 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
LV686508
ABM
1.0 ug DNA
EUR 616.8
HES7 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)
LV623138
ABM
1.0 ug DNA
EUR 616.8
HES3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)
LV672266
ABM
1.0 ug DNA
EUR 616.8
HES2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)
LV672368
ABM
1.0 ug DNA
EUR 616.8
HES1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)
LV686504
ABM
1.0 ug DNA
EUR 616.8
HES7 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
LV623139
ABM
1.0 ug DNA
EUR 686.4
HES7 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
LV623140
ABM
1.0 ug DNA
EUR 686.4
HES3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
LV672267
ABM
1.0 ug DNA
EUR 686.4
HES3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
LV672268
ABM
1.0 ug DNA
EUR 686.4
HES2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
LV672369
ABM
1.0 ug DNA
EUR 686.4
HES2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
LV672370
ABM
1.0 ug DNA
EUR 686.4
HES1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
LV686505
ABM
1.0 ug DNA
EUR 686.4
HES1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
LV686506
ABM
1.0 ug DNA
EUR 686.4
HESX1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV623557
ABM
1.0 ug DNA
EUR 616.8
HESX1 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV623561
ABM
1.0 ug DNA
EUR 616.8
HESX1 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
LV623562
ABM
1.0 ug DNA
EUR 616.8
Hes7 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL704389
Origene Technologies GmbH
5 µg/vial
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Hes6 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL701920
Origene Technologies GmbH
5 µg/vial
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Hes2 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL710249
Origene Technologies GmbH
5 µg/vial
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Hes3 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL710817
Origene Technologies GmbH
5 µg/vial
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Hes1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL711022
Origene Technologies GmbH
5 µg/vial
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HES4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL304123
Origene Technologies GmbH
5 µg/vial
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Hes7 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL513783
Origene Technologies GmbH
5 µg/vial
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Hes2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL512897
Origene Technologies GmbH
5 µg/vial
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HES1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL312478
Origene Technologies GmbH
5 µg/vial
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HES2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL317232
Origene Technologies GmbH
5 µg/vial
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HES6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL317296
Origene Technologies GmbH
5 µg/vial
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Hes6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL509996
Origene Technologies GmbH
5 µg/vial
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Hes3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL510622
Origene Technologies GmbH
5 µg/vial
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HES3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL318488
Origene Technologies GmbH
5 µg/vial
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Hes1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL500947
Origene Technologies GmbH
5 µg/vial
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HES7 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL317637
Origene Technologies GmbH
5 µg/vial
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HESX1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)
LV623558
ABM
1.0 ug DNA
EUR 616.8
HESX1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
LV623559
ABM
1.0 ug DNA
EUR 686.4
HESX1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
LV623560
ABM
1.0 ug DNA
EUR 686.4
Hesx1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL707619
Origene Technologies GmbH
5 µg/vial
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HESX1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL312476
Origene Technologies GmbH
5 µg/vial
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Hesx1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL512112
Origene Technologies GmbH
5 µg/vial
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CD Lentiviral Vector
LV678
ABM
10 μg
EUR 950
Hes5 ORF Vector (Rat) (pORF)
ORF068156
ABM
1.0 ug DNA
EUR 607.2
HES5 ORF Vector (Human) (pORF)
ORF020694
ABM
1.0 ug DNA
EUR 486
Hes5 ORF Vector (Mouse) (pORF)
ORF047114
ABM
1.0 ug DNA
EUR 607.2
Cas9 Nickase Lentiviral Vector
K005
ABM
10 ug
EUR 135
Description: N/A
dCas9-KRAB Lentiviral Vector
K203
ABM
10 ug
EUR 165
Description: N/A
Cas9 Nuclease Lentiviral Vector
K002
ABM
10 ug
EUR 135
Description: N/A
dCas9-TET1CD Lentiviral Vector
K096
ABM
10 µg, Titer: N/A
EUR 395
Description: N/A
dCas9-DNMT3A Lentiviral Vector
K091
ABM
10 µg, Titer: N/A
EUR 395
Description: N/A
Green Kit. Baculovirus GFP vector.
K20
AB Vector LLC
1 Kit
EUR 695
Description: Protein expression
ProGreen. Baculovirus GFP marker vector.
A1
AB Vector LLC
25 ul
EUR 420
Description: Protein expression
Cas9 Double Mutant Lentiviral Vector
K012
ABM
10 ug
EUR 395
Description: N/A
Luciferase-mCherry Lentiviral Vector (CMV)
LV010138
ABM
1.0 μg
EUR 230
ESR1 Lentiviral Vector (Human) (pLenti-II)
LV010008
ABM
1.0 ug DNA
EUR 379.2
HES5 Protein Vector (Rat) (pPM-C-HA)
PV272624
ABM
500 ng
EUR 723.6
pLenti-GFP Lentiviral Control Vector
LTV-400
Cell Biolabs
100 µL
EUR 420
pLenti-GFP Lentiviral Control Vector
MBS168202-01mL
MyBiosource
0.1mL
EUR 660
pLenti-GFP Lentiviral Control Vector
MBS168202-5x01mL
MyBiosource
5x0.1mL
EUR 2795
HES5 Protein Vector (Rat) (pPB-C-His)
PV272622
ABM
500 ng
EUR 723.6
HES5 Protein Vector (Rat) (pPB-N-His)
PV272623
ABM
500 ng
EUR 723.6
HES5 Protein Vector (Rat) (pPM-C-His)
PV272625
ABM
500 ng
EUR 723.6
Hes5 - Rat shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.
TL711044V
Origene Technologies GmbH
500 ul each
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HES5 - Human shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.
TL312477V
Origene Technologies GmbH
500 ul each
Ask for price
Hes5 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.
TL500948V
Origene Technologies GmbH
500 ul each
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HES5 Protein Vector (Mouse) (pPM-C-HA)
PV188456
ABM
500 ng
EUR 723.6
HES5 Protein Vector (Human) (pPM-C-HA)
PV082775
ABM
500 ng
EUR 662.4
ProEasy. Vector for easy construction of recombinant baculoviruses.
A10S
AB Vector LLC
25 ul
EUR 695
Description: Protein expression
HES5 Protein Vector (Mouse) (pPM-C-His)
PV188457
ABM
500 ng
EUR 723.6
HES5 Protein Vector (Mouse) (pPB-C-His)
PV188454
ABM
500 ng
EUR 723.6
HES5 Protein Vector (Mouse) (pPB-N-His)
PV188455
ABM
500 ng
EUR 723.6
HES5 Protein Vector (Human) (pPB-C-His)
PV082773
ABM
500 ng
EUR 662.4
HES5 Protein Vector (Human) (pPB-N-His)
PV082774
ABM
500 ng
EUR 662.4
HES5 Protein Vector (Human) (pPM-C-His)
PV082776
ABM
500 ng
EUR 662.4
pLenti-MCS Lentiviral Expression Vector
LV000
ALSTEM
10 µg
EUR 416.5
pSMPUW-Neo Lentiviral Expression Vector
MBS169522-001mg
MyBiosource
0.01mg
EUR 665
pSMPUW-Neo Lentiviral Expression Vector
MBS169522-5x001mg
MyBiosource
5x0.01mg
EUR 2825
pSMPUW-Neo Lentiviral Expression Vector
VPK-213
Cell Biolabs
10 µg
EUR 424
pSMPUW-Puro Lentiviral Expression Vector
MBS169521-001mg
MyBiosource
0.01mg
EUR 665
pSMPUW-Puro Lentiviral Expression Vector
MBS169521-5x001mg
MyBiosource
5x0.01mg
EUR 2825
pSMPUW-Puro Lentiviral Expression Vector
VPK-212
Cell Biolabs
10 µg
EUR 424
pSMPUW-MNDnLacZ Lentiviral Control Vector
LTV-402
Cell Biolabs
10 µg
EUR 741.6
Description: Use this control vector to co-transfect along with lentivirus packaging vectors to make a recombinant control lentivirus.
pSMPUW-Hygro Lentiviral Expression Vector
MBS169523-001mg
MyBiosource
0.01mg
EUR 665
pSMPUW-Hygro Lentiviral Expression Vector
MBS169523-5x001mg
MyBiosource
5x0.01mg
EUR 2825
pSMPUW-Hygro Lentiviral Expression Vector
VPK-214
Cell Biolabs
10 µg
EUR 505
pAB-bee. Baculovirus plasmid vector for secreted and transmembrane proteins.
B3
AB Vector LLC
50 ul
EUR 495
Description: Protein expression
XK Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658357
ABM
1.0 ug DNA
EUR 818.4
XK Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658361
ABM
1.0 ug DNA
EUR 818.4
GC Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658465
ABM
1.0 ug DNA
EUR 818.4
GC Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658469
ABM
1.0 ug DNA
EUR 818.4
G4 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659323
ABM
1.0 ug DNA
EUR 616.8
G4 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659327
ABM
1.0 ug DNA
EUR 616.8
TF Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV652363
ABM
1.0 ug DNA
EUR 1626
TF Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV652367
ABM
1.0 ug DNA
EUR 1626
C2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV655195
ABM
1.0 ug DNA
EUR 1626
C2 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV655199
ABM
1.0 ug DNA
EUR 1626
F7 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV666001
ABM
1.0 ug DNA
EUR 818.4
F7 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV666005
ABM
1.0 ug DNA
EUR 818.4
FH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV666085
ABM
1.0 ug DNA
EUR 818.4
FH Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV666089
ABM
1.0 ug DNA
EUR 818.4
F9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV667969
ABM
1.0 ug DNA
EUR 818.4
F9 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV667973
ABM
1.0 ug DNA
EUR 818.4
F5 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV628711
ABM
1.0 ug DNA
EUR 3850.8
F5 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV628715
ABM
1.0 ug DNA
EUR 3850.8
N5 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV626671
ABM
1.0 ug DNA
EUR 616.8
N5 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV626675
ABM
1.0 ug DNA
EUR 616.8
F8 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV648325
ABM
1.0 ug DNA
EUR 4111.2
F8 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV648329
ABM
1.0 ug DNA
EUR 4111.2
T Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV639319
ABM
1.0 ug DNA
EUR 818.4
T Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV639323
ABM
1.0 ug DNA
EUR 818.4
C9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV677989
ABM
1.0 ug DNA
EUR 818.4
C9 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV677993
ABM
1.0 ug DNA
EUR 818.4
TG Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV679015
ABM
1.0 ug DNA
EUR 4963.2
TG Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV679019
ABM
1.0 ug DNA
EUR 4963.2
CS Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV679231
ABM
1.0 ug DNA
EUR 818.4
CS Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV679235
ABM
1.0 ug DNA
EUR 818.4
AR Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV675175
ABM
1.0 ug DNA
EUR 1626
AR Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV675179
ABM
1.0 ug DNA
EUR 1626
CP Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV676159
ABM
1.0 ug DNA
EUR 1626
CP Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV676163
ABM
1.0 ug DNA
EUR 1626
HP Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV683065
ABM
1.0 ug DNA
EUR 818.4
HP Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV683069
ABM
1.0 ug DNA
EUR 818.4
F3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV693439
ABM
1.0 ug DNA
EUR 616.8
F3 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV693443
ABM
1.0 ug DNA
EUR 616.8
SI Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV694363
ABM
1.0 ug DNA
EUR 3415.2
SI Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV694367
ABM
1.0 ug DNA
EUR 3415.2
MB Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV694681
ABM
1.0 ug DNA
EUR 616.8
MB Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV694685
ABM
1.0 ug DNA
EUR 616.8
F2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV698257
ABM
1.0 ug DNA
EUR 818.4
F2 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV698261
ABM
1.0 ug DNA
EUR 818.4
HR Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV698527
ABM
1.0 ug DNA
EUR 1626
HR Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV698531
ABM
1.0 ug DNA
EUR 1626
TH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV699655
ABM
1.0 ug DNA
EUR 818.4
TH Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV699659
ABM
1.0 ug DNA
EUR 818.4
C3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV688795
ABM
1.0 ug DNA
EUR 3117.6
C3 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV688799
ABM
1.0 ug DNA
EUR 3117.6
GK Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV688915
ABM
1.0 ug DNA
EUR 818.4
GK Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV688919
ABM
1.0 ug DNA
EUR 818.4
C6 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV673381
ABM
1.0 ug DNA
EUR 1626
C6 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV673385
ABM
1.0 ug DNA
EUR 1626
KL Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV673531
ABM
1.0 ug DNA
EUR 1626
KL Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV673535
ABM
1.0 ug DNA
EUR 1626
Qk Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV686425
ABM
1.0 ug DNA
EUR 616.8
Qk Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV686429
ABM
1.0 ug DNA
EUR 616.8
PC Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV696073
ABM
1.0 ug DNA
EUR 1626
PC Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV696077
ABM
1.0 ug DNA
EUR 1626
IK Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV696211
ABM
1.0 ug DNA
EUR 818.4
IK Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV696215
ABM
1.0 ug DNA
EUR 818.4
EOS Lentiviral Vector (PL-SIN-EOS-C(3)-EiP)
LV028858
ABM
1.0 µg DNA
EUR 215
EOS Lentiviral Vector (PL-SIN-EOS-S(4)-EiP)
LV028859
ABM
1.0 ug DNA
EUR 215
RP9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV620767
ABM
1.0 ug DNA
EUR 616.8
RP9 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV620771
ABM
1.0 ug DNA
EUR 616.8
C8G Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV620785
ABM
1.0 ug DNA
EUR 616.8
C8G Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV620789
ABM
1.0 ug DNA
EUR 616.8
JRK Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV622183
ABM
1.0 ug DNA
EUR 818.4
JRK Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV622187
ABM
1.0 ug DNA
EUR 818.4
ADO Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV622783
ABM
1.0 ug DNA
EUR 616.8
ADO Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV622787
ABM
1.0 ug DNA
EUR 616.8
MGP Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV657865
ABM
1.0 ug DNA
EUR 616.8
MGP Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV657869
ABM
1.0 ug DNA
EUR 616.8
ELN Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658267
ABM
1.0 ug DNA
EUR 1626
ELN Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658271
ABM
1.0 ug DNA
EUR 1626
SET Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658291
ABM
1.0 ug DNA
EUR 616.8
SET Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658295
ABM
1.0 ug DNA
EUR 616.8
FAU Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658567
ABM
1.0 ug DNA
EUR 616.8
FAU Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658571
ABM
1.0 ug DNA
EUR 616.8
C4B Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658867
ABM
1.0 ug DNA
EUR 3241.2
C4B Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658871
ABM
1.0 ug DNA
EUR 3241.2
DYM Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659185
ABM
1.0 ug DNA
EUR 1626
DYM Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659189
ABM
1.0 ug DNA
EUR 1626
FAU Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659317
ABM
1.0 ug DNA
EUR 616.8
FAU Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659321
ABM
1.0 ug DNA
EUR 616.8
AFP Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659371
ABM
1.0 ug DNA
EUR 818.4
AFP Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659375
ABM
1.0 ug DNA
EUR 818.4
GRP Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659401
ABM
1.0 ug DNA
EUR 616.8
GRP Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659405
ABM
1.0 ug DNA
EUR 616.8
HLX Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659761
ABM
1.0 ug DNA
EUR 818.4
HLX Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659765
ABM
1.0 ug DNA
EUR 818.4
FTO Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659851
ABM
1.0 ug DNA
EUR 818.4
FTO Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659855
ABM
1.0 ug DNA
EUR 818.4
MAK Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659869
ABM
1.0 ug DNA
EUR 818.4
MAK Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659873
ABM
1.0 ug DNA
EUR 818.4
MFF Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659875
ABM
1.0 ug DNA
EUR 616.8
MFF Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659879
ABM
1.0 ug DNA
EUR 616.8
PIR Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV660103
ABM
1.0 ug DNA
EUR 616.8
PIR Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV660107
ABM
1.0 ug DNA
EUR 616.8
Most of the vaccines beneath improvement for COVID-19 contain the usage of viral vectors. The Brighton Collaboration Profit-Danger Evaluation of Vaccines by Expertise (BRAVATO, previously the Viral Vector Vaccine Security Working Group, V3SWG)
working group has ready a standardized template to explain the important thing concerns for the benefit-risk evaluation of viral vector vaccines.
It will facilitate key stakeholders to anticipate potential issues of safety and interpret or assess security information. This might additionally assist enhance communication and public acceptance of licensed viral vector vaccines.
Accelerating the Morphogenetic Cycle of the Viral Vector Aedes aegypti Larvae for Quicker Larvicidal Bioassays
Any bioassay to check new chemically synthesized larvicides or phytolarvicides in opposition to
Culicidae and extra dangerous mosquito species, comparable to
Aede s aegypti and Aedes albopictus , which particularly transmit dengue, yellow fever, chikungunya viral fevers in addition to Zika virus, or
Anopheles gambiae , a vector for malaria and philariasis, requires 1000’s of well-developed larvae, ideally on the fourth instar stage. The pure morphogenetic cycle of
Aedes spp., within the discipline or within the laboratory, could lengthen to 19 days at room temperature (e.g., 25°C) from the primary everlasting contact between viable eggs and water and the final stage of larval progress or metamorphosis into flying adults.
Thus, accelerated sequential molting is fascinating for swifter bioassays of larvicides. We achieved this objective in
Aedes aegypti with very restricted strategic and low-cost additions to meals, comparable to coconut water, milk or its casein, yeast extract, and to a lesser extent, glycerol. The naturally wealthy coconut water was glorious for rapidly attaining the inhabitants of instar IV larvae, essentially the most superior one earlier than pupation, saving a couple of week, for subsequent larvicidal bioassays. Diluted milk, as one other meals supply, allowed a good quicker last ecdysis and adults are helpful for mosquito taxonomical objective.
Dpf1 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL704327
Origene Technologies GmbH
5 µg/vial
Ask for price
DPF1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL313388
Origene Technologies GmbH
5 µg/vial
Ask for price
Dpf1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL502763
Origene Technologies GmbH
5 µg/vial
Ask for price
Dpf2 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL707052
Origene Technologies GmbH
5 µg/vial
Ask for price
Dpf3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL515258
Origene Technologies GmbH
5 µg/vial
Ask for price
DPF3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL313386
Origene Technologies GmbH
5 µg/vial
Ask for price
DPF2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL313387
Origene Technologies GmbH
5 µg/vial
Ask for price
Dpf2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector
TL501886
Origene Technologies GmbH
5 µg/vial
Ask for price
Dpf1 ORF Vector (Rat) (pORF)
ORF066188
ABM
1.0 ug DNA
EUR 607.2
DPF1 ORF Vector (Human) (pORF)
ORF012873
ABM
1.0 ug DNA
EUR 114
Dpf1 ORF Vector (Mouse) (pORF)
ORF043301
ABM
1.0 ug DNA
EUR 607.2
CD Lentiviral Vector
LV678
ABM
10 μg
EUR 950
Cas9 Nickase Lentiviral Vector
K005
ABM
10 ug
EUR 135
Description: N/A
dCas9-KRAB Lentiviral Vector
K203
ABM
10 ug
EUR 165
Description: N/A
Cas9 Nuclease Lentiviral Vector
K002
ABM
10 ug
EUR 135
Description: N/A
dCas9-TET1CD Lentiviral Vector
K096
ABM
10 µg, Titer: N/A
EUR 395
Description: N/A
dCas9-DNMT3A Lentiviral Vector
K091
ABM
10 µg, Titer: N/A
EUR 395
Description: N/A
DPF1 Protein Vector (Rat) (pPM-C-HA)
PV264752
ABM
500 ng
EUR 723.6
DPF1 Protein Vector (Rat) (pPB-C-His)
PV264750
ABM
500 ng
EUR 723.6
DPF1 Protein Vector (Rat) (pPB-N-His)
PV264751
ABM
500 ng
EUR 723.6
DPF1 Protein Vector (Rat) (pPM-C-His)
PV264753
ABM
500 ng
EUR 723.6
DPF1 Protein Vector (Mouse) (pPM-C-HA)
PV173204
ABM
500 ng
EUR 723.6
DPF1 Protein Vector (Human) (pPM-C-HA)
PV051491
ABM
500 ng
EUR 577.2
DPF1 Protein Vector (Mouse) (pPB-C-His)
PV173202
ABM
500 ng
EUR 723.6
DPF1 Protein Vector (Mouse) (pPB-N-His)
PV173203
ABM
500 ng
EUR 723.6
DPF1 Protein Vector (Mouse) (pPM-C-His)
PV173205
ABM
500 ng
EUR 723.6
DPF1 Protein Vector (Human) (pPB-C-His)
PV051489
ABM
500 ng
EUR 577.2
DPF1 Protein Vector (Human) (pPB-N-His)
PV051490
ABM
500 ng
EUR 577.2
DPF1 Protein Vector (Human) (pPM-C-His)
PV051492
ABM
500 ng
EUR 577.2
Dpf1 - Rat shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.
TL704327V
Origene Technologies GmbH
500 ul each
Ask for price
DPF1 - Human shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.
TL313388V
Origene Technologies GmbH
500 ul each
Ask for price
Dpf1 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.
TL502763V
Origene Technologies GmbH
500 ul each
Ask for price
Green Kit. Baculovirus GFP vector.
K20
AB Vector LLC
1 Kit
EUR 695
Description: Protein expression
ProGreen. Baculovirus GFP marker vector.
A1
AB Vector LLC
25 ul
EUR 420
Description: Protein expression
Cas9 Double Mutant Lentiviral Vector
K012
ABM
10 ug
EUR 395
Description: N/A
Luciferase-mCherry Lentiviral Vector (CMV)
LV010138
ABM
1.0 μg
EUR 230
ESR1 Lentiviral Vector (Human) (pLenti-II)
LV010008
ABM
1.0 ug DNA
EUR 379.2
pLenti-GFP Lentiviral Control Vector
LTV-400
Cell Biolabs
100 µL
EUR 420
pLenti-GFP Lentiviral Control Vector
MBS168202-01mL
MyBiosource
0.1mL
EUR 660
pLenti-GFP Lentiviral Control Vector
MBS168202-5x01mL
MyBiosource
5x0.1mL
EUR 2795
ProEasy. Vector for easy construction of recombinant baculoviruses.
A10S
AB Vector LLC
25 ul
EUR 695
Description: Protein expression
pLenti-MCS Lentiviral Expression Vector
LV000
ALSTEM
10 µg
EUR 416.5
pSMPUW-Neo Lentiviral Expression Vector
MBS169522-001mg
MyBiosource
0.01mg
EUR 665
pSMPUW-Neo Lentiviral Expression Vector
MBS169522-5x001mg
MyBiosource
5x0.01mg
EUR 2825
pSMPUW-Neo Lentiviral Expression Vector
VPK-213
Cell Biolabs
10 µg
EUR 424
pSMPUW-Puro Lentiviral Expression Vector
MBS169521-001mg
MyBiosource
0.01mg
EUR 665
pSMPUW-Puro Lentiviral Expression Vector
MBS169521-5x001mg
MyBiosource
5x0.01mg
EUR 2825
pSMPUW-Puro Lentiviral Expression Vector
VPK-212
Cell Biolabs
10 µg
EUR 424
pSMPUW-MNDnLacZ Lentiviral Control Vector
LTV-402
Cell Biolabs
10 µg
EUR 741.6
Description: Use this control vector to co-transfect along with lentivirus packaging vectors to make a recombinant control lentivirus.
pSMPUW-Hygro Lentiviral Expression Vector
MBS169523-001mg
MyBiosource
0.01mg
EUR 665
pSMPUW-Hygro Lentiviral Expression Vector
MBS169523-5x001mg
MyBiosource
5x0.01mg
EUR 2825
pSMPUW-Hygro Lentiviral Expression Vector
VPK-214
Cell Biolabs
10 µg
EUR 505
pAB-bee. Baculovirus plasmid vector for secreted and transmembrane proteins.
B3
AB Vector LLC
50 ul
EUR 495
Description: Protein expression
XK Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658357
ABM
1.0 ug DNA
EUR 818.4
XK Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658361
ABM
1.0 ug DNA
EUR 818.4
GC Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658465
ABM
1.0 ug DNA
EUR 818.4
GC Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658469
ABM
1.0 ug DNA
EUR 818.4
G4 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV659323
ABM
1.0 ug DNA
EUR 616.8
G4 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV659327
ABM
1.0 ug DNA
EUR 616.8
TF Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV652363
ABM
1.0 ug DNA
EUR 1626
TF Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV652367
ABM
1.0 ug DNA
EUR 1626
C2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV655195
ABM
1.0 ug DNA
EUR 1626
C2 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV655199
ABM
1.0 ug DNA
EUR 1626
F7 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV666001
ABM
1.0 ug DNA
EUR 818.4
F7 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV666005
ABM
1.0 ug DNA
EUR 818.4
FH Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV666085
ABM
1.0 ug DNA
EUR 818.4
FH Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV666089
ABM
1.0 ug DNA
EUR 818.4
F9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV667969
ABM
1.0 ug DNA
EUR 818.4
F9 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV667973
ABM
1.0 ug DNA
EUR 818.4
F5 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV628711
ABM
1.0 ug DNA
EUR 3850.8
F5 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV628715
ABM
1.0 ug DNA
EUR 3850.8
N5 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV626671
ABM
1.0 ug DNA
EUR 616.8
N5 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV626675
ABM
1.0 ug DNA
EUR 616.8
F8 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV648325
ABM
1.0 ug DNA
EUR 4111.2
F8 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV648329
ABM
1.0 ug DNA
EUR 4111.2